Additionally, GLP-1 RAs modulate the hypothalamus (the region in the brain that controls appetite) to regulate hunger, slow gastric emptying, and regulate gut hormones such as leptin (a hormone that helps regulate body weight on a long-term basis)
Patients considering GLP-1 receptor agonist or dual GIP/GLP-1 therapy should understand that these medications facilitate weight loss through appetite reduction and decreased food intake, not by "speeding up metabolism" or burning additional calories at rest
Peptides 126 , 170234 (2020)
Results from two studies found no association between the use of GLP-1 receptor agonists and increased risk for suicide, suicidal thoughts or depression, findings published in JAMA Internal Medicine showed
How to support hair health while on GLP-1s If youre experiencing hair shedding during treatment, there are evidence-based steps you can take to support your body through this transition: Nutritional Support: Prioritise protein intake aim for 6080g daily if youre losing weight, focusing on complete proteins like lean meats, fish, eggs, and legumes Maintain consistent multivitamin supplementation , especially important when eating less Monitor key nutrients request blood tests for iron, zinc, B12, and vitamin D levels through your GP Lifestyle Modifications: Manage stress effectively through adequate sleep (7-9 hours), mindfulness practices, or gentle exercise Stay well-hydrated aim for at least 2 litres of water daily Consider gentle hair care use mild shampoos, avoid excessive heat styling, and be gentle when brushing Professional Support: Consult a trichologist or dermatologist for specialised hair loss assessment Discuss topical treatments like minoxidil with a healthcare professional Consider scalp massage to improve circulation Important: Never discontinue your GLP-1 medication without consulting your healthcare provider
